Being overweight can increase the risk of cardiovascular disease at a young age

Physicians are studying the effects of an increased BMI in young people
Obesity and obesity often lead to health problems. Researchers have now found that an increased body mass index (BMI) can contribute to the development of cardiovascular disease at a young age. Young people over the age of 17 are more likely to suffer from cardiovascular health problems if they are overweight.

The University of Bristol researchers found that there is a link between an increased BMI and the development of cardiovascular disease. The doctors published the results of their study in the journal "Alpha Galileo".

Experts analyze the data from more than 14,000 parents and children
The results of the current study were presented at the Conference of the European Society of Human Genetics. The experts used the statistics of the Avon Longitudinal Study of Parents and Children (ALSPAC) for their investigation. This study is a worldwide leading birth cohort study that began in the early 1990s involving more than 14,000 pregnant mothers and their partners and children. The scientists discovered that the cardiovascular threat increased due to the higher BMI values ​​and was likely to occur earlier in life.

Doctors find a common indicator of heart disease
The team was able to use the genomic information from the ALSPAC study to determine the relationship between higher blood pressure and the left ventricular mass index (LVMI) between the ages of 17 and 21. The thickening (hypertrophy) of the left ventricular wall in the heart means that the heart has to work harder to pump blood. This is a common indicator of various heart conditions.

What is the effect of an increased BMI on the performance of the heart?
The causal influence of the higher BMI on cardiac output, which was only driven by the blood volume of the left ventricle, could at least partially explain why the higher BMI affects cardiac hypertrophy and blood pressure, says author Dr. Calf.

For the first time, doctors have identified a heart risk in young people
The results of the scientific study support efforts to prevent obesity at a young age in order to prevent the development of cardiovascular changes. The current study made it possible for the first time to observe such a connection in a group of young adults, explains Dr. Calf. So an improved conclusion about the cause was possible.

Overweight and obesity should be combated in youth
While randomized controlled trials are very important for the unbundling of cause and effect in diseases, these studies are unfortunately usually expensive, time-consuming and labor-intensive, says the author However, modern genomics make it possible to identify causality more quickly and cost-effectively, and the availability of large amounts of genetic data means that previous limits of observational epidemiological studies can be overcome, the expert adds. We hope that the current study will lead to increased efforts to combat obesity in early life, the researchers concluded. (as)

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Video: Obesity and Heart Disease (October 2021).