Obesity and type 2 diabetes increase the risk of liver cancer

The BMI and diabetes have a huge impact on our risk of liver cancer
Many people in the world have problems with their weight. Obesity and obesity have been linked to a variety of diseases. Researchers have now found that people with an excessively high Body Mass Index (BMI) and type 2 diabetes are 2.61 times more likely to develop liver cancer.

The American Cancer Society scientists found in their investigation that the link between high BMI and type 2 diabetes leads to an increased likelihood of liver cancer. The doctors published the results of their study in the journal "Cancer Research".

As the BMI increases, the risk of liver cancer increases
The identified risk of liver cancer increased as the body mass index increased, the researchers report. For every five centimeters that those affected increase in waist circumference, the risk of liver cancer increases by eight percent, the experts warn.

The rates of liver cancer will continue to increase
In the United States, liver cancer rates have roughly tripled since the mid-1970s, explains the author Dr. Peter Campbell of the American Cancer Society. Unfortunately, the prognosis for patients with liver cancer is mostly very poor. So far, liver cancer has been a relatively rare form of cancer. However, liver cancer rates will increase in the future as a result of the amount of alcohol consumed and the rise in obesity, the researchers say.

Study analyzes data from approximately 1.57 million Americans
For their investigation, the researchers analyzed the data from 14 different studies of approximately 1.57 million American adults. Before starting the study, all participants had to fill out questionnaires about their height, weight, alcohol consumption, tobacco consumption and other factors related to cancer risk.

Over 2,100 subjects developed liver cancer
Participants were diagnosed with type 2 diabetes in 6.5 percent. Over time, 2,162 of the participating subjects developed liver cancer, the authors say. Generally, people should be aware that signs and symptoms of diabetes are not always obvious. The illnesses are often only diagnosed when visiting a doctor.

Symptoms of diabetes
How can sufferers know that they may have diabetes? Noticeable symptoms include, for example, frequent urination, especially at night. Another indicator could be frequent fatigue, the doctors explain. If you are often thirsty and drink a lot, it can also be a symptom of type 1 and type 2 diabetes. Some sufferers also lose weight very quickly without knowing exactly why. Another symptom may be an itch around the penis or vagina, but it's important to have it examined by a doctor, the scientists add.

Risk factors for an increased risk of liver cancer
The researchers compared the rates of liver cancer among participants with or without obesity and diabetes. The experts wanted to determine the relative risk of liver cancer. Each of these factors could be associated with the risk of liver cancer. All factors relate to so-called metabolic dysfunctions, explains Dr. Campbell. People should make sure that they keep their body weight in the normal range.

Current results are supported by older data
The results are also in line with other data. These had already indicated that obesity and diabetes could play an important role in the rapid increase in liver cancer in recent decades, says author Dr. Campbell.

Diabetes leads to a more than doubled risk of liver cancer
The lifelong risk of liver cancer in the United States is around one percent. About eight adults in 100,000 adults develop liver cancer each year. Adults with type 2 diabetes have an increased risk of developing liver cancer, the doctors say. Your risk is more than twice that of people without diabetes.

Study results are important for public health
The results are very important for public health, because obesity and diabetes are unfortunately common, common risk factors across the population, explains co-author Dr. Katherine A McGlynn of the National Cancer Institute. While some other well-described risk factors, such as hepatitis B virus or hepatitis C virus, are associated with an increased risk of liver cancer, these factors are far less common than obesity and diabetes, the doctor adds. (as)

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