Prostate cancer: red wine has a slightly protective effect
Prostate cancer is the most common cancer in German men and the third most common cause of cancer death. According to estimates by the Robert Koch Institute (RKI), far more than 60,000 men in Germany contract a malignant tumor of the prostate every year. Over 12,000 die from prostate cancer each year. An international team of researchers has now determined that moderate red wine consumption can have a slightly protective effect.
Moderate red wine consumption can be healthy
According to experts, red wine can be healthy - if consumed in moderation. Studies have shown that the polyphenol resveratrol contained in red wine has positive effects in diseases such as hardening of the arteries (arteriosclerosis), Alzheimer's, arthritis or heart diseases. An international team of researchers has now discovered another possible positive effect of polyphenols.
The most common of all cancers
As the Medical University (MedUni) Vienna reports, prostate cancer is the most common of all cancers in the western world.
15 to 20 percent of men are affected at some point in their lives, 2.6 percent die from prostate cancer.
In addition to genetic, environmental (epigenetic) risk factors are also involved in the development of prostate cancer; evidence of this includes smoking, increased sugar consumption or that of red meat.
An international team of researchers led by Shahrokh Shariat, head of the University Clinic for Urology at MedUni Vienna, has now examined the risk factor of wine consumption in a meta-analysis - with a somewhat surprising result.
Slightly protective effect
According to the scientists, moderate wine consumption generally does not significantly increase the risk. Moderate red wine enjoyment even has a slightly protective effect.
According to Shariat, “moderate” means about a glass a day.
It could be shown that the risk is not significantly increased if the other risk factors are taken into account and not smoked or not too much sugar or red meat is consumed.
Furthermore, the retrospective investigation of 17 high-quality studies with around 611,000 patients showed that moderate red wine consumption has a slightly protective effect.
"This reduced the risk of developing prostate cancer by around 12 percent, while the consumption of white wine increased the risk by 26 percent," said Shariat.
The results of the study were recently published in the clinical journal "Clinical Epidemiology".
The researchers now want to find out which ingredients in red wine have this protective effect and whether it can also be used preventively for therapeutic purposes - for example for high-risk groups.
"It has already been shown in other diseases and cancers that polyphenols, which are mainly contained in red wine, can have a protective effect," said the urologist.
The concentration in red wine is 10 times higher than in white wine, which could be a reason for the results observed.
In addition, the European Food Authority has confirmed that polyphenol-containing olive oil helps protect blood lipids from oxidative stress.
Positive effects of polyphenols on an accumulation of platelets in the arteries and on insulin sensitivity have also been shown.
“It is possible that the polyphenols from the red wine can be used preventively. The question is: what can we learn from the results of the study - and how can we use it in science and preventive medicine? ”(Ad)