Ibuprofen pain reliever can potentially cause male infertility

Popular pain reliever: Ibuprofen can possibly damage male fertility

Recently, Danish scientists reported a study that paracetamol can lead to premature infertility in women. Apparently, another pain reliever can affect reproductive performance: According to an international team of researchers, ibuprofen may possibly damage male fertility.

Over-the-counter pain relievers with side effects

With a mild fever, quickly take a paracetamol tablet and swallow an ibuprofen for a headache: Many people assume that such pain relievers are harmless because they are available for sale. But such careless handling of supposedly harmless products can be dangerous. The health risks of such preparations, such as stomach upset, have long been known. Even the risk of cardiac arrest can be increased by some means. However, it was not previously known that ibuprofen may also affect male fertility.

Impaired fertility due to ibuprofen intake

Men who take high doses of ibuprofen for months could be at greater risk of fertility problems and other health problems such as muscle loss, erectile dysfunction, and fatigue.

An international team of researchers found that out.

The study, published in the journal Proceedings of the National Academy of Sciences (PNAS), showed that prolonged use of the drug disrupted the production of male sex hormones.

Production of male sex hormones is disrupted

According to a report by the British newspaper "The Guardian", the researchers observed in healthy subjects between the ages of 18 and 35 that the drug disrupted the production of male sex hormones and led to a disorder in men known as "compensated hypogonadism", a condition that is usually seen in older men and smokers.

The level of the so-called luteinizing hormone rose in the study participants who swallowed 600 mg ibuprofen twice a day. The male body uses this to regulate the production of testosterone.

According to the experts, the increase suggests that the drug causes problems in certain cells in the testicles and prevents them from producing testosterone, which is naturally required for the production of sperm.

Long-term use could lead to permanently low testosterone levels

Doctors in Copenhagen, who led the study, said the volunteers' disability was mild and temporary, but they feared that long-term use could lead to permanently low testosterone levels.

"Our immediate concern is the horror of men who use the drug for a long period of time," David Møbjerg Kristensen of the University of Copenhagen told the Guardian.

"These preparations are good pain relievers, but some people in society use them without considering them as real medicines."

Do not take medication for months

Study author Bernard Jégou of the French National Institute for Health and Medical Research said he sees no problem in people taking ibuprofen to relieve pain such as toothache in the short term, but warned against taking the drug for months when it is not absolutely necessary .

"We are concerned, especially about healthy people who do not have to take these drugs. The risk is greater than the benefit, ”said Jégou.

William Colledge, a professor of reproductive physiology at the University of Cambridge, who was not involved in the study, said: “It is a fascinating study that suggests that men should be careful when consuming high doses of ibuprofen for long periods of time. "

Although the results would have to be confirmed in further studies, he himself made a resolution: "Based on this data, I would personally be very reluctant to take ibuprofen longer than the 10 days normally specified on the package." (Ad)

Author and source information

Video: What Causes Male Fertility Problems? Male Infertility Explained (November 2021).